HCID 2732509, compound → HCID 13304107, compound

HRID 1979821Notes

Reaction equation

HRID 1979821 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[CH:11]([CH3:14])[S:10][CH:9]2[C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[CH:4][CH:3]=1>C(OCC)C>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[C:12](=[O:13])[CH:11]([CH3:14])[S:10][CH:9]2[C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 2732509HCID 2732509, compound

Product 1

HCID 13304107HCID 13304107, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 4 g. of 3-(4-chlorophenyl)-5-methyl-2-(3-pyridyl)-4-thiazolidinone (Example 1, supra) in ethyl ether was prepared, filtered and saturated with anhydrous hydrogen chloride. The solid material which precipitated was filtered off and identified by NMR spectrum as 3-(4-chlorophenyl)-5-methyl-2-(3-pyridyl)-4-thiazolidinone hydrochloride. The melting point of the product was about 135° C.

Workup

  1. filtrationfiltered and saturated with anhydrous hydrogen chloride
  2. customThe solid material which precipitated
  3. filtrationwas filtered off
  4. customwas about 135° C.

Sources & evidence

ORD record
ord-1819a6c04fed4a1da984cc75f52ae735
Source dataset
uspto-grants-1984_11
Patent number
US04482712

Reaction notes

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