HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → 3-[4-(Hexadecylamino)benzoyl]-4-carboethoxythiazolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethyl thiazolidine-4-carboxylate | HCID 103574 | — |
| Reactant | 4-Hexadecylaminobenzoyl chloride hydrochloride | HCID 13255322 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-[4-(Hexadecylamino)benzoyl]-4-carboethoxythiazolidine | HCID 20437342 | — |
Reaction Steps
One-tenth mole of 4-(hexadecylamino)benzoyl chloride hydrochloride in methylene chloride is added to a solution of 0.1 mole of ethyl thiazolidine-4-carboxylate in chloroform containing two equivalents of triethylamine. After 5 hours at 20° C. the solution is filtered and evaporated to a white solid which is recrystallized from acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04485105 |
| Source dataset | uspto-grants-1984_11 |
| ORD ID | ord-47fe206ddad44a95b5cb045531ee3cf0 |
| Source note | uspto-grants-1984_11 |