HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenethylamine → HCID 70480714, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenethylamine | HCID 1001 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Isobutyl cyanoacetate | HCID 25918 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Product | HCID 70480714 | HCID 70480714 | — |
Reaction Steps
Isobutyl cyanoacetate (5.8 g), benzylmethylamine (7 ml), triethyl orthoformate (14 ml) and p-toluenesulphonic acid (5 mg) were heated under reflux for 1 hour. The cooled reaction mixture was triturated with petroleum ether (bp 40°-60° C.) and the solid filtered off. Recrystallisation from ethanol gave isobutyl 3-(benzylmethylamino)-2-cyano-2-propenoate, m.p. 105°-106° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04508659 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-25a301d9c294464cb6b544f68b16b5cc |
| Source note | uspto-grants-1985_04 |