HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13423950, compound → HCID 13423951, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13423950 | HCID 13423950 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 13423951 | HCID 13423951 | 91.2% |
Reaction Steps
A solution of 10.0 g (0.0305 mole) of 1-benzyl-3-(2-ethoxyphenoxy)methyl-3-pyrrolidinol in 125 ml of absolute ethanol was treated with Pd/C catalyst and warmed while shaking under a hydrogen atmosphere on a Parr hydrogenation apparatus for 16 hours. The catalyst was removed by filtration and the filtrate evaporated under reduced pressure. The white crystalline residue (7.1 g) was recrystallized from benzene isooctane to yield 6.6 g of product (91%), m.p. 108°-110° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04508724 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-542dd287f1774dedb2e81c61ad093770 |
| Source note | uspto-grants-1985_04 |