HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Indoline-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Indoline | HCID 10328 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Product | Indoline-2-carboxylic acid | HCID 86074 | — |
Reaction Steps
31.5 g of the above indoline (86%) are obtained by saponification in 250 ml of normal sodium hydroxide solution and 150 ml of ethanol for 18 hours at room temperature of 43 g (0.224 mol) of the corresponding ethyl ester prepared according to E. J. COREY et al. (J. Amer. Chem. Soc. 1970 92, p. 2476).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04508729 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-b9a559f9b22c4f1986cc9bc214acb566 |
| Source note | uspto-grants-1985_04 |