HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → 7-(1-Phenyl-3-dimethylaminopropoxy)-isoflavone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | 7-(1Phenyl-3-methylaminopropoxy)-isoflavone | HCID 12918915 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 7-(1-Phenyl-3-dimethylaminopropoxy)-isoflavone | HCID 12918914 | — |
Reaction Steps
30 g of formic acid, is added dropwise to 38.5 g of 7-(1-phenyl-3-methylaminopropoxy)-isoflavone, while stirring and cooling, and 7 g of 25% formaldehyde solution is then added dropwise at 20°. The mixture is heated on a waterbath until evolution of gas ceases and is cooled, poured onto ice and worked up in the customary manner to give 7-(1-phenyl-3-dimethylaminopropoxy)-isoflavone. M.p. 128°-130°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04508732 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-a8c55e48697f4abd8e46f4ab9e90b9e8 |
| Source note | uspto-grants-1985_04 |