HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 1-benzyl 5-tert-butyl (5S)-3-benzyl-2-oxoimidazolidine-1,5-dicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-benzyl 5-tert-butyl (5S)-2-oxoimidazolidine-1,5-dicarboxylate | HCID 11067160 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-benzyl 5-tert-butyl (5S)-3-benzyl-2-oxoimidazolidine-1,5-dicarboxylate | HCID 56635970 | 75.6% |
Reaction Steps
A mixture of 9.6 g of tert.-butyl (4S)-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate, 8.3 g of potassium carbonate, 20 g of benzyl bromide and 200 ml of acetone is stirred at room temperature for 3 days. Then, the reaction mixture is treated in the same manner as described in Preparation 1-(2). 9.3 g of tert.-butyl (4S)-1-benzyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate are obtained as colorless viscous oil. Yield: 75.6%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04508727 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-e71425bd9235467fab9c33c957336003 |
| Source note | uspto-grants-1985_04 |