HCID 13477747, compound → HCID 13477726, compound

HRID 1980300Notes

Reaction equation

HRID 1980300 reaction equation
[CH3:1][N:2]1[CH2:6][C@@H:5]([C:7]([O:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:8])[N:4](C(OCC2C=CC=CC=2)=O)[C:3]1=[O:27]>Br.C(O)(=O)C>[CH3:1][N:2]1[CH2:6][C@@H:5]([C:7]([O:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:8])[NH:4][C:3]1=[O:27]

Participants

3

Reactant 1

HCID 13477747HCID 13477747, compound

Product 1

HCID 13477726HCID 13477726, compoundYield 83.3%

Reagents, catalysts & solvents 1

HCID 21893785Acetic Acid Mixture with Hydrobromic AcidSolvent

Procedure

10 g of benzyl (4S)-1-methyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate and 40 ml of a hydrogen bromide-acetic acid solution are treated in the same manner as described in Preparation 4-(3), whereby 5.3 g of benzyl (4S)-1-methyl-2-oxo-imidazolidine-4-carboxylate are obtained as colorless crystals. Yield: 83.3%

Workup

  1. customas described in Preparation 4-(3)

Sources & evidence

ORD record
ord-4aaf6d1f81f54388843835a86b8974e2
Source dataset
uspto-grants-1985_04
Patent number
US04508727

Reaction notes

Loading…