HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorobenzoyl isocyanate → 1-(2-Chlorobenzoyl)-3-(4,6-dimethyl-5-phenyl-2-pyridyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorobenzoyl isocyanate | HCID 9942311 | — |
| Reactant | 4,6-Dimethyl-5-phenyl-2-pyridylamine | HCID 13502854 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-(2-Chlorobenzoyl)-3-(4,6-dimethyl-5-phenyl-2-pyridyl)urea | HCID 13242652 | — |
Reaction Steps
4,6-Dimethyl-5-phenyl-2-pyridylamine (0.5 gram) was dissolved in 25 ml acetonitrile and reacted with 2-chlorobenzoyl isocyanate (0.6 gram) under nitrogen at room temperature. A precipitate formed immediately and the reaction was stirred for approximately 2 hours. The solid product was collected, washed with a small amount of acetonitrile, and identified by NMR as the desired product, m.p. 176°-189° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04508722 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-a5acc5c442474f24a22ba48eb84a819c |
| Source note | uspto-grants-1985_04 |