HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-(4-chlorophenyl)nicotinonitrile → 6-(4-Chlorophenyl)pyridine-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-(4-chlorophenyl)nicotinonitrile | HCID 2765233 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 6-(4-Chlorophenyl)pyridine-3-carbonitrile | HCID 14823234 | — |
Reaction Steps
2-Chloro-6-(4-chlorophenyl)-3-pyridinecarbonitrile (2.49 grams) and 5% Pd/C (0.3 gram) were reacted on a Parr shaker in 100 ml DMF. Next the reaction mixture was filtered and the filtrate poured into ice water. A solid formed which was collected and recrystallized from ethanol, yield 0.85 gram.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04508722 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-8e1ba7e0ecdf46c1859b536a5f961eab |
| Source note | uspto-grants-1985_04 |