反应详情

5-Methyl-6-phenyl-3-pyridylamine (0.4 gram) in 20 ml of acetonitrile was added to 2,6-dichlorobenzoyl isocyanate (0.5 gram) under nitrogen and at room temperature. After about 10-20 minutes a precipitate formed. The reaction mixture was then stirred for about 4-5 hours and the product was filtered and washed with acetonitrile, yield, 580 mg, m.p. 202°-205° C. A small portion of the product was recrystallized from ethanol, m.p. 204°-209° C.

1. customAfter about 10-20 minutes a precipitate formed
2. filtrationthe product was filtered
3. washwashed with acetonitrile
4. customyield
5. customA small portion of the product was recrystallized from ethanol, m.p. 204°-209° C.