HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → N-methyl-N-p-fluorobenzyl-m-fluoroaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | 4-Fluorobenzyl chloride | HCID 9602 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 3-fluoro-N-methylaniline | HCID 2759011 | — |
| Product | N-methyl-N-p-fluorobenzyl-m-fluoroaniline | HCID 14008648 | — |
Reaction Steps
N-methyl-N-p-fluorobenzyl-m-fluoroaniline was prepared from 26.3 grams (0.21 mole) of N-methyl-m-fluoroaniline, 30.6 grams (0.21 mole) p-fluorobenzyl chloride (Aldrich), 17.8 grams anhydrous sodium acetate and 0.18 grams iodine according to the procedure described in Example III. Yield 35.4 grams (72 percent), boiling point 131°-137° C. at 0.2 mmHg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04508803 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-f4d6602696fc43f4928d91f2214859a8 |
| Source note | uspto-grants-1985_04 |