HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → Ethyl 4-[4-(4-trifluoromethylphenoxy)phenoxy]-3-phenylamino-2-pentenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | Ethyl 4-[4-(4-trifluoromethylphenoxy)phenoxy]-3-oxopentanoate | HCID 13469151 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | Ethyl 4-[4-(4-trifluoromethylphenoxy)phenoxy]-3-phenylamino-2-pentenoate | HCID 70489003 | — |
Reaction Steps
Using the procedure of Reynolds and Hauser, Org. Syn. Coll. Vol 3, a mixture of ethyl 4-[4-(4-trifluoromethylphenoxy)phenoxy]-3-oxopentanoate (1.51 g), benzene (15 ml) and aniline (0.5 g) is azeotropically distilled. The reaction product is purified using a florisil column and eluting with hexane/ethylacetate (9:1) to yield (fractions 2, 3 and 4) ethyl 4-[4-(4-trifluoromethylphenoxy)phenoxy]-3-phenylamino-2-pentenoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04508906 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-9aad0bcfdac54a00bd3a288cc18349e7 |
| Source note | uspto-grants-1985_04 |