反应详情

温度

110 °C

1420 g of 1-(p-tert.butylphenyl)-2-formyl-1-propene, prepared as described in paragraph (e), are mixed together with 6 g of 5% palladium/carbon and 6.8 g of soda in 20 ml of water at 70°-75° C. in a stirring autoclave. The autoclave is charged with hydrogen (8 atmospheres) and heated to 110° C. About 230 liters of hydrogen are absorbed after 12 hours. The crude 3-(p-tert.butyl-phenyl)-2-methyl-propionaldehyde is treated with ether, washed neutral with water and dried over sodium sulphate. After removing the ether, the product is fractionally distilled in vacuo. After separating a first running and a last running, there are obtained 1275 g of 3-(p-tert.butyl-phenyl)-2-methyl-propionaldehyde in 95% purity (about 88% of theory). Boiling point: 150°-152° C./15 mmHg; nD20 =1.5050.

1. customAbout 230 liters of hydrogen are absorbed after 12 hours
2. additionThe crude 3-(p-tert.butyl-phenyl)-2-methyl-propionaldehyde is treated with ether
3. washwashed neutral with water
4. dry with materialdried over sodium sulphate
5. customAfter removing the ether
6. distillationthe product is fractionally distilled in vacuo
7. customAfter separating a first running