Benzoyl chloride → HCID 20402882, compound

HRID 1980402Notes

Reaction equation

HRID 1980402 reaction equation
[NH:1]1[C:6]2([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:12](Cl)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>N1C=CC=CC=1>[C:12]([N:1]1[C:6]2([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 7412Benzoyl chlorideHCID 573583HCID 573583, compound

Product 1

HCID 20402882HCID 20402882, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The 1-azaspiro[5.5]undecane starting material can be prepared by the method described by H. Hodjat, et al., in J. Heterocyclic Chem., 9, 1081 (1972). This starting material is treated with benzoyl chloride in pyridine to form the N-benzoyl-1-azaspiro-[5.5]undecane, shown at the beginning of step 2.

Sources & evidence

ORD record
ord-307fd9a818f246b6a06f9c4e7cbab81a
Source dataset
uspto-grants-1985_04
Patent number
US04508911

Reaction notes

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