HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonic Acid → HCID 20402459, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonic Acid | HCID 6395 | — |
| Reactant | HCID 20402460 | HCID 20402460 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 20402459 | HCID 20402459 | 50% |
Reaction Steps
2-Benzhydryloxycarbonyl-7-t-butoxycarbonylamino-8-oxo-3-[2-(pyridin-4-yl)-thiazol-5-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene 5-oxide (6.4 g) is treated with methanesulphonic acid (6 cc) in acetonitrile (60 cc) in accordance with the procedure of Example 2 to give 7-amino-2-benzhydryloxycarbonyl-8-oxo-3-[2-(pyridin-4-yl)thiazol-5-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene 5-oxide (2.7 g) in the form of a hard brown foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04508717 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-8d90e6afb1e447228d0978e44699e4f2 |
| Source note | uspto-grants-1985_04 |