m-Chloroperbenzoic acid → HCID 20402460, compound

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Reaction Steps

A solution of 2-benzhydryloxycarbonyl-7-t-butoxycarbonylamino-8-oxo-3-[2-(pyridin-4-yl)-thiazol-5-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene (24 g) in methylene chloride (370 cc) is oxidised with 85% pure meta-chloroperbenzoic acid (7.92 g) in accordance with the procedure described in Example 2 to give 2-benzhydryloxycarbonyl-7-t-butoxycarbonylamino-8-oxo-3-[2-(pyridin-4-yl)-thiazol-5-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene 5-oxide (23 g) in the form of a brown-yellow solid.

Provenance & Evidence