HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropyl Ether → HCID 13206546, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropyl Ether | HCID 7914 | — |
| Reactant | Benzenesulfonyl isocyanate, 2-chloro- | HCID 174071 | — |
| Reactant | 4-methoxypteridin-2-amine | HCID 246283 | — |
| Catalyst | Triethylamine | HCID 8471 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 13206546 | HCID 13206546 | 87% |
Reaction Steps
1.5 g (0.0069 mol) of 2-amino-4-methoxypteridine and two drops of triethylamine were added to a mixture of 1.77 g (0.01 mol) of 2-chlorophenylsulfonyl isocyanate in 20 ml of acetonitrile and the mixture was refluxed for 30 minutes, cooled and mixed with diisopropyl ether. After standing for 10 minutes, the mixture was vacuum filtered to obtain 2.25 g (87% of theory) of N-(4-methoxypteridin-2-yl)-N'-(2-chlorophenylsulfonyl)-urea melting at 212° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04509972 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-b39d55fcc183422d8e5ffb6047752d74 |
| Source note | uspto-grants-1985_04 |