Benzoic acid, 2-(isocyanatosulfonyl)-, methyl ester → HCID 13206552, compound

Participants

Reaction Steps

A mixture of 1.3 g (0.0068 mol) of 2-amino-4-dimethylaminopteridine and 1.7 g of 2-methoxycarbonylphenylsulfonyl isocyanate in 40 ml of acetonitrile was refluxed for 4 hours and the hot mixture was vacuum filtered to obtain 2.5 g (85% of theory) of N-(4-dimethylaminopteridin-2-yl)-N'-(2-methoxycarbonylphenylsulfonyl)-urea in the form of brownish crystals melting at 219° C.

Provenance & Evidence