ethyl 2-[P-ethyl-2-hydroxyamino-5-(2-chloro-4-trifluoromethylphenoxy)phenylphosphinyloxyimino]propionate → ethyl 2-[P-ethyl-2-nitroso-5-(2-chloro-4-trifluoromethylphenoxy)phenylphosphinyloxyimino]propionate

Participants

Reaction Steps

A mixture of ethyl 2-[P-ethyl-2-hydroxyamino-5-(2-chloro-4-trifluoromethylphenoxy)phenylphosphinyloxyimino]propionate (400 mmol) and ferric chloride (600 mmol) in aqueous ethanol (1:3 water:ethanol; 10 ml) is stirred at RT for 10 min. The reaction is filtered and the filtrate is diluted with methylene chloride, washed, dried and evaporated to dryness to give ethyl 2-[P-ethyl-2-nitroso-5-(2-chloro-4-trifluoromethylphenoxy)phenylphosphinyloxyimino]propionate.

Provenance & Evidence