Acetic Anhydride → HCID 13336537, compound

Participants

Reaction Steps

1.58 g of 2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazole-1-yl methyl)-thiazolidine prepared in the same manner as in Working Example 1 except that β-mercaptoethylamine hydrochloride was used instead of β-mercapto-β-methyl-ethylamine hydrochloride, was mixed with 2.0 g of acetic anhydride, and the mixture was reacted at 120° C. for 4 hours. After the reaction, the reaction product was purified by silica gel column chromatography using a solvent mixture of chloroform and methanol as the developer, whereby 0.6 g of 2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazole-1-yl methyl)-3-acetyl thiazolidine (Compound No. 48 in Table 1) was obtained.

Provenance & Evidence