HCID 13519238, compound → HCID 13519245, compound

Participants

Reaction Steps

using 98.50 g (0.168 mol) of [2-(N-ethoxycarbonyl-3-(trifluoromethyl)-phenylamino)-phenylazo]-(2-chloroacetamido)-malonic acid diethyl ester there is obtained crude 1-[2-[N-ethoxycarbonyl-3-(trifluoromethyl)-phenylamino]-phenyl]-5-(chloromethyl)-1H-1,2,4-triazole-3-carboxylic acid which sinters from 88° and melts at 100°-108° with decomposition; using 91.10 g (0.166 mol) of [2-(N-ethoxycarbonyl-2,3-dimethylphenylamino)-phenylazo]-(2-chloroacetamido)-malonic acid diethyl ester there is obtained crude 1-[2-(N-ethoxycarbonyl-2,3-dimethylphenylamino)-phenyl]-5-(chloromethyl)-1H-1,2,4-triazole-3-carboxylic acid which melts at 188°-190° with decomposition;

Provenance & Evidence