4-Chloroaniline → HCID 20401827, compound

Participants

Reaction Steps

using 8.91 g (0.033 mol) of 1-(2-chloro-3-pyridyl)-5-(chloromethyl)-1H-1,2,4-triazole-3-carboxylic acid and 20.90 g (0.164 mol) of p-chloroaniline there is obtained 5-(4-chlorophenyl)-4,5-dihydropyrido[2,3-e][1,2,4]triazolo[1,5-a]pyrazine-2-carboxylic acid and the methyl ester thereof which, after recrystallisation from methylene chloride/ethyl acetate, melts at 234°-237° with decomposition;

Provenance & Evidence