Sodium borohydride → HCID 13519280, compound

HRID 1980559Notes

Reaction equation

C[O:2][C:3]([C:5]1[N:24]=[C:8]2[CH2:9][N:10]([C:17]3[CH:22]=[CH:21][CH:20]=[C:19]([Cl:23])[CH:18]=3)[C:11]3[N:16]=[CH:15][CH:14]=[CH:13][C:12]=3[N:7]2[N:6]=1)=O.[BH4-].[Na+]>>[Cl:23][C:19]1[CH:18]=[C:17]([N:10]2[C:11]3[N:16]=[CH:15][CH:14]=[CH:13][C:12]=3[N:7]3[N:6]=[C:5]([CH2:3][OH:2])[N:24]=[C:8]3[CH2:9]2)[CH:22]=[CH:21][CH:20]=1

Participants

Reactant 2

HCID 4311764Sodium borohydride

HCID 13519267HCID 13519267, compound

Product 1

HCID 13519280HCID 13519280, compound

Procedure

using 3.80 g (0.011 mol) of 5-(3-chlorophenyl)-4,5-dihydropyrido[2,3-e][1,2,4]triazolo[1,5-a]pyrazine-2-carboxylic acid methyl ester and 4.20 g (0.112 mol) of sodium borohydride there is obtained 5-(3-chlorophenyl)-4,5-dihydropyrido[2,3-e][1,2,4]triazolo[1,5-a]pyrazine-2-methanol having a melting point of 204°-206°;

Sources & evidence

ORD record: ord-43f7379e7f024c82b91dbd5093bd3073
Source dataset: uspto-grants-1985_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04510141

Reaction notes

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