Sodium borohydride → HCID 13519281, compound

HRID 1980560Notes

Reaction equation

HRID 1980560 reaction equation
C[O:2][C:3]([C:5]1[N:24]=[C:8]2[CH2:9][N:10]([C:17]3[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=3)[C:11]3[N:16]=[CH:15][CH:14]=[CH:13][C:12]=3[N:7]2[N:6]=1)=O.[BH4-].[Na+]>>[Cl:23][C:20]1[CH:19]=[CH:18][C:17]([N:10]2[C:11]3[N:16]=[CH:15][CH:14]=[CH:13][C:12]=3[N:7]3[N:6]=[C:5]([CH2:3][OH:2])[N:24]=[C:8]3[CH2:9]2)=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 4311764Sodium borohydrideHCID 13519268HCID 13519268, compound

Product 1

HCID 13519281HCID 13519281, compound

Procedure

using 7.90 g (0.023 mol) of 5-(4-chlorophenyl)-4,5-dihydropyrido[2,3-e][1,2,4]triazolo[1,5-a]pyrazine-2-carboxylic acid methyl ester and 4.37 g (0.116 mol) of sodium borohydride there is obtained 5-(4-chlorophenyl)-4,5-dihydropyrido[2,3-e][1,2,4]triazolo[1,5-a]pyrazine-2-methanol having a melting point of 240°-245° with decomposition;

Sources & evidence

ORD record
ord-8b06dc5d9ef24a9fbeca4f6f9790c215
Source dataset
uspto-grants-1985_04
Patent number
US04510141

Reaction notes

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