Sodium Hydroxide → HCID 178433673, compound

HRID 1980655Notes

Reaction equation

HRID 1980655 reaction equation
[CH3:1][C:2]1[NH:6][CH:5]=[N:4][C:3]=1[CH2:7][S:8][CH2:9][CH2:10][NH:11][C:12]1[C:16]([O:17]C)=[N:15][S:14](=[O:20])(=[O:19])[N:13]=1.[OH-].[Na+]>CO>[OH:17][C:16]1[C:12]([NH:11][CH2:10][CH2:9][S:8][CH2:7][C:3]2[N:4]=[CH:5][NH:6][C:2]=2[CH3:1])=[N:13][S:14](=[O:19])(=[O:20])[N:15]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 1784943354-methoxy-N-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]-1,1-dioxo-1,2,5-thiadiazol-3-amine

Product 1

HCID 178433673HCID 178433673, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

When a methanolic solution of 3-{2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethylamino}-4-methoxy-1,2,5-thiadiazole 1,1-dioxide [prepared by the procedure of Step A of Example 1] is treated with a solution of sodium hydroxide in methanol by the general procedure of Example 17, Step B, the title compound is produced, mp 263°-265° (dec).

Sources & evidence

ORD record
ord-91435c4002544d08ba5748ca854bb395
Source dataset
uspto-grants-1985_04
Patent number
US04510309

Reaction notes

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