Ammonia → HCID 136446069, compound

HRID 1980812Notes

Reaction equation

HRID 1980812 reaction equation
[C:1]([C:3]1[C:4](=[O:17])[NH:5][C:6]2[CH2:7][CH2:8][C:9]3[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=3[C:11]=2[CH:12]=1)#[N:2].[Cl-:18].[NH4+:19].N>>[ClH:18].[CH:12]1[C:11]2[C:10]3[CH:13]=[CH:14][CH:15]=[CH:16][C:9]=3[CH2:8][CH2:7][C:6]=2[NH:5][C:4](=[O:17])[C:3]=1[C:1]([NH2:19])=[NH:2]

Participants

4

Reactant 3

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 20400737HCID 20400737, compound

Product 1

HCID 136446069HCID 136446069, compound

Conditions

Temperature
80 °C

Procedure

Add 2.10 gm of 2-cyano-5,6-dihydrobenzo[f]quinolin-3(4H)-one to 0.53 gm of ammonium chloride in liquid ammonia in a steel bomb. Heat the system to 80° C. for 24 hours. Cool the system to room temperature and remove the ammonia. Isolate 5,6-dihydrobenzo[f]quinolin-3(4H)-one-2-carboxamidine hydrochloride.

Workup

  1. temperatureCool the system to room temperature
  2. customremove the ammonia

Sources & evidence

ORD record
ord-f667c08bcc6e455291aadcdef99fd71e
Source dataset
uspto-grants-1985_04
Patent number
US04511569

Reaction notes

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