Pyridine → HCID 20400758, compound

HRID 1980814Notes

Reaction equation

HRID 1980814 reaction equation
[NH2:1][C:2]1[C:3](=[O:16])[NH:4][C:5]2[CH2:6][CH2:7][C:8]3[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=3[C:10]=2[CH:11]=1.N1C=CC=CC=1.[C:23](Cl)(=[O:25])[CH3:24]>C(Cl)(Cl)Cl>[C:23]([NH:1][C:2]1[C:3](=[O:16])[NH:4][C:5]2[CH2:6][CH2:7][C:8]3[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=3[C:10]=2[CH:11]=1)(=[O:25])[CH3:24]

Participants

5

Reactant 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 20400712HCID 20400712, compound

Product 1

HCID 20400758HCID 20400758, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To 2.0 gm of 2-amino-5,6-dihydrobenzo[f]quinolin-3(4H)-one, in 100 ml of chloroform containing 1 ml of pyridine add 0.80 gm of acetyl chloride. Stir the reaction at room temperature for 5 hours. Filter and wash the solution with water. Remove the solvent by stripping to give the title compound.

Workup

  1. customthe reaction at room temperature for 5 hours
  2. filtrationFilter
  3. washwash the solution with water
  4. customRemove the solvent

Sources & evidence

ORD record
ord-db81b99c3ed84b4c8d33b1772436e226
Source dataset
uspto-grants-1985_04
Patent number
US04511569

Reaction notes

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