Chlorine → HCID 20400735, compound

HRID 1980816Notes

Reaction equation

HRID 1980816 reaction equation
[CH:1]1[C:10]2[C:9]3[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=3[CH2:7][CH2:6][C:5]=2[NH:4][C:3](=[O:15])[CH:2]=1.[Cl:16]Cl>C(O)(=O)C>[Cl:16][C:2]1[C:3](=[O:15])[NH:4][C:5]2[CH2:6][CH2:7][C:8]3[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=3[C:10]=2[CH:1]=1

Participants

4

Reactant 2

HCID 24526ChlorineHCID 10631790HCID 10631790, compound

Product 1

HCID 20400735HCID 20400735, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Add 19.7 gm of 5,6-dihydrobenzo[f]quinolin-3(4H)-one to 300 ml of acetic acid. Bubble chlorine into the reaction solution for 4 hours at 100°. Cool the system and collect the product as a precipate. Dissolve the solid into water and neutralize the solution with 1N NaOH. Extract the product with chloroform. Dry the chloroform over anhydrous magnesium sulfate and filter the solution. Remove the solvent by stripping to give the title compound.

Workup

  1. temperatureCool the system
  2. customcollect the product as a precipate
  3. dissolutionDissolve the solid into water
  4. extractionExtract the product with chloroform
  5. dry with materialDry the chloroform over anhydrous magnesium sulfate
  6. filtrationfilter the solution
  7. customRemove the solvent

Sources & evidence

ORD record
ord-5481f5a8bc994dbf96c6df7f1a3b3541
Source dataset
uspto-grants-1985_04
Patent number
US04511569

Reaction notes

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