反应详情

4,4-Dimethylpentanoic acid (40 g; Chem Lett, (1980), 571) was treated at 20° for 16 h with thionyl chloride (40 g) and the mixture distilled under reduced pressure to yield 4,4-dimethylpentanoyl chloride (38 g) b.p. 52°-58° at 10 mm Hg; δ (CDCl3) 0.94 (9H,s,C(CH3)3 ; 1.66 (2H,t,J=9 Hz,CH2) and 2.88 (2H,t,J=9 Hz,CH2CO).

1. distillationthe mixture distilled under reduced pressure