HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20400800, compound → 5-Chloro-1-methyl-2-(3-pyridyl)-3-indolehexanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20400800 | HCID 20400800 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 5-Chloro-1-methyl-2-(3-pyridyl)-3-indolehexanoic acid | HCID 129518 | — |
Reaction Steps
A mixture of 1.0 g of 5-chloro-3-[5-(ethoxycarbonyl)pentyl]-1-methyl-2-(3-pyridyl)indole in 20 ml of 2N aqueous hydrochloride acid is stirred and heated at reflux overnight. The mixture is cooled and the solid formed collected and dried in vacuo to give 5-chloro-3-(5-carboxypentyl)-1-methyl-2-(3-pyridyl)indole hydrochloride, m.p. 186°-189°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04511573 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-43051af7c6044a1a875f8f3d90ab3e37 |
| Source note | uspto-grants-1985_04 |