HRID19809

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2773751

3-Chloro-2-fluoro-5-(trifluoromethyl)benzoic acid

C8H3ClF4O2

结构：CC(C)(C)c1ccc(CNCCc2cccc(OCc3ccccc3)c2)cc1

HCID68562248

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)c1ccc(CN(CCc2cccc(OCc3ccccc3)c2)C(=O)c2cc(C(F)(F)F)cc(Cl)c2F)cc1

HCID68562844

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in analogy to Example 1, using [2-(3-benzyloxy-phenyl)-ethyl]-(4-tert-butyl-benzyl)-amine (S9-C43) and 3-chloro-2-fluoro-5-(trifluoromethyl)benzoic acid. MS: 597.3 [ISP (M+H)+].

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-08484c243e8f477eb532cc0ed5a8f40b
来源数据集: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07745477B2
来源说明: uspto-grants-2010_06

反应 SMILES

[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][NH:17][CH2:18][C:19]2[CH:24]=[CH:23][C:22]([C:25]([CH3:28])([CH3:27])[CH3:26])=[CH:21][CH:20]=2)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:29][C:30]1[C:31]([F:43])=[C:32]([CH:36]=[C:37]([C:39]([F:42])([F:41])[F:40])[CH:38]=1)[C:33](O)=[O:34]>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][N:17]([CH2:18][C:19]2[CH:24]=[CH:23][C:22]([C:25]([CH3:28])([CH3:27])[CH3:26])=[CH:21][CH:20]=2)[C:33](=[O:34])[C:32]2[CH:36]=[C:37]([C:39]([F:40])([F:41])[F:42])[CH:38]=[C:30]([Cl:29])[C:31]=2[F:43])[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1