Water → 3,3-Dimethyl-5-oxohexanoic acid

Participants

Reaction Steps

A solution of 16 g of isophorone in 100 g of dichloromethane was cooled down to 0° C. A stream of oxygen, which contained about 4 percent of ozone, was conducted through this solution until the solution was saturated with ozone. Then the ozonolyzed solution was added drop by drop into 150 ml of boiling water, the dichloromethane was distilled off and the aqueous solution was boiled for another 3 hours. The 3,3-dimethyl-5-oxo-hexanoic acid formed was isolated by reducing under vacuum.

Provenance & Evidence