Ethyl Acetate → Triphenylphosphine Oxide

Participants

Reaction Steps

Through a mixture of triphenylphosphine sulfide (11.03 g) and ethyl acetate (200 ml) is bubbled chlorine gas (ca. 2.2 molar equivalents) at room temperature. The resulting mixture is neutralized with aqueous 6% sodium hydrogen carbonate (350 ml) and stirred at room temperature for 10 minutes. The reaction mixture is then worked up as in the case of Example 1 to give triphenylphosphine oxide (10 g). m.p. 154°-157° C.

Provenance & Evidence