HCID 20399851, compound → HCID 13472125, compound

HRID 1981134Notes

Reaction equation

HRID 1981134 reaction equation
[N:1]([CH2:4][CH2:5][CH2:6][C:7]([N:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12][CH2:11][CH2:10]1)=O)=[N+]=[N-].[H-].[Al+3].[Li+].[H-].[H-].[H-]>CCOCC.O>[NH2:1][CH2:4][CH2:5][CH2:6][CH2:7][N:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12][CH2:11][CH2:10]1

Participants

5

Reactant 2

HCID 20399851HCID 20399851, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 13472125HCID 13472125, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 3283Diethyl EtherSolvent

Procedure

The 1-(4-azidobutanoyl)-1,2,3,4-tetrahydroquinoline (3.9 g) was refluxed in ether containing lithium aluminium hydride (1.8 g) for 5 hours. The solution was cooled and diluted cautiously with water. The organic phase was washed, dried and evaporated to afford the title compound as an oil, which was then converted to the dimaleate mp 79°-81°.

Workup

  1. temperatureThe solution was cooled
  2. washThe organic phase was washed
  3. customdried
  4. customevaporated

Sources & evidence

ORD record
ord-8a937896d9914b0bb307326e68f1eff5
Source dataset
uspto-grants-1985_04
Patent number
US04512990

Reaction notes

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