HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3S)-3-Benzoylamino-1-chloro-4-phenyl-2-butanone → tetrahydro-6-[[3-(benzoylamino)-2-oxo-4-phenylbutyl]amino]-5-oxo-1,4-thiazepine-4(5H)-acetic acid, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3S)-3-Benzoylamino-1-chloro-4-phenyl-2-butanone | HCID 13339657 | — |
| Reactant | 6-Amino-tetrahydro-5-oxo-1,4-thiazepine-4(5H)-acetic acid, ethyl ester, hydrochloride | HCID 131714191 | — |
| Product | tetrahydro-6-[[3-(benzoylamino)-2-oxo-4-phenylbutyl]amino]-5-oxo-1,4-thiazepine-4(5H)-acetic acid, ethyl ester | HCID 86740032 | — |
Reaction Steps
6-Amino-tetrahydro-5-oxo-1,4-thiazepine-4(5H)-acetic acid, ethyl ester, hydrochloride is reacted with (S)-N-[3-chloro-2-oxo-1-(phenylmethyl)propyl]benzamide according to the procedure of Example 1(h) to give tetrahydro-6-[[3-(benzoylamino)-2-oxo-4-phenylbutyl]amino]-5-oxo-1,4-thiazepine-4(5H)-acetic acid, ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04512988 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-99196fb3e8cf4869aded150c3985f401 |
| Source note | uspto-grants-1985_04 |