HCID 53774082, compound → HCID 12217345, compound

Participants

Reaction Steps

Ethyl α-(3,4-dimethoxybenzylidene)acetoacetate (50 g) was catalytically reduced in a Parr low pressure apparatus in ethyl acetate (150 ml) in the presence of 5% palladium on charcoal catalyst (Pd/C)(3 g). The catalyst was removed by filtration; the solvent was removed under reduced pressure; and the residual oil was distilled to give ethyl α-(3,4-dimethoxybenzyl)-acetoacetate (40.5 g, b.p. 162°-164° C./0.4 mm Hg).

Provenance & Evidence