Thionyl Chloride → HCID 53743491, compound

HRID 1981187Notes

Reaction equation

HRID 1981187 reaction equation
[CH:1]1[C:11]2[CH2:10][CH2:9][C:8]3[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=3[CH:6]([CH2:16][C:17]([OH:19])=O)[C:5]=2[CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:22])=O>C1C=CC=CC=1>[CH:1]1[C:11]2[CH2:10][CH2:9][C:8]3[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=3[CH:6]([CH2:16][C:17]([Cl:22])=[O:19])[C:5]=2[CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 1266909110,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylacetic acid

Product 1

HCID 53743491HCID 53743491, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 160 g of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene-5-acetic acid and 230 ml of thionyl chloride is heated to boiling under reflux for 2.5 hours. After concentration of the mixture in vacuo, the residue is treated twice with 300 ml of dry benzene each time and in each case evaporated to dryness. 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-acetic acid chloride is obtained as a red-brown oil.

Workup

  1. temperatureis heated
  2. temperatureunder reflux for 2.5 hours
  3. customin each case evaporated to dryness

Sources & evidence

ORD record
ord-3a33fca8b18042d3b3b049bb9a51d635
Source dataset
uspto-grants-1985_04
Patent number
US04513002

Reaction notes

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