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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 19812Generated: October 25, 2026

1-Propylboronic acid → N-(4-tert-butyl-benzyl)-3-chloro-5-propyl-N-[2-(3-trifluoromethyl-phenyl)-ethyl]-benzamide

https://huagongshe.com/reaction/19812

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Propylboronic acidHCID 351065—
Reactant3-bromo-N-(4-tert-butyl-benzyl)-5-chloro-N-[2-(3-trifluoromethyl-phenyl)-ethyl]-benzamideHCID 68561614—
ProductN-(4-tert-butyl-benzyl)-3-chloro-5-propyl-N-[2-(3-trifluoromethyl-phenyl)-ethyl]-benzamideHCID 68559834—

Reaction Steps

The title compound was prepared in analogy to example 3, using 3-bromo-N-(4-tert-butyl-benzyl)-5-chloro-N-[2-(3-trifluoromethyl-phenyl)-ethyl]-benzamide (Example B176) and n-propylboronic acid. 516.2 [ISP (M+H)+]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07745477B2
Source datasetuspto-grants-2010_06
ORD IDord-9bb4ecb6e2ca42ea91dd9b2ee2c3f691
Source noteuspto-grants-2010_06