Methanol → HCID 13105362, compound

HRID 1981215Notes

Reaction equation

HRID 1981215 reaction equation
[C:1]1([CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11][CH2:12][CH2:13][C:14]([OH:16])=[O:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(=O)(=O)(O)O.[CH3:22]O>>[C:1]1([CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11][CH2:12][CH2:13][C:14]([O:16][CH3:22])=[O:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 13105329HCID 13105329, compound

Product 1

HCID 13105362HCID 13105362, compound

Procedure

A solution of (Z)-8-phenyl-5-octenoic acid (12.6 g), see Example 1(a), and concentrated sulphuric acid (0.1 ml) in methanol (300 ml) was heated under reflux for 2 hours. The solution was evaporated and the residue distilled under vacuum to give the ester b.p. 110° to 113° C./0.1 mm.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 2 hours
  3. customThe solution was evaporated
  4. distillationthe residue distilled under vacuum

Sources & evidence

ORD record
ord-6c55d75a4fc2452c83fc43fc9307c2cf
Source dataset
uspto-grants-1985_04
Patent number
US04513005

Reaction notes

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