Pyridine → HCID 20400421, compound

Participants

Reaction Steps

A mixture of 7,8-dihydroxy-2-methylchromone-3-carboxylic acid (0.9 g), dimethylformamide (10 ml), pyridine (0.92 ml) and acetic anhydride (1.2 ml) was stirred at room temperature for 4 hours. Ethyl acetate (100 ml) was added to the liquid reaction mixture, and the organic layer was washed successively with 6N-HCl and water, and then dried over anhydrous magnesium sulfate. The solvent was evaporated and ethyl ether was added to the residue. The resulting solid was collected by filtration and then washed with a 1:1 mixed solvent of ethyl acetate and ethyl ether, followed by drying to afford the desired product (0.534 g).

Provenance & Evidence