Dichloromethane → HCID 20398788, compound

HRID 1981256Notes

Reaction equation

[Cl:1]Cl.[CH2:3]([O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[S:13]([NH:16][C:17]([NH:19][C:20]1[N:25]=[C:24]([O:26][CH3:27])[N:23]=[C:22]([CH3:28])[N:21]=1)=[O:18])(=[O:15])=[O:14])[CH:4]=C.[CH2:29]([Cl:31])Cl>>[Cl:1][CH:4]([CH2:29][Cl:31])[CH2:3][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[S:13]([NH:16][C:17]([NH:19][C:20]1[N:25]=[C:24]([O:26][CH3:27])[N:23]=[C:22]([CH3:28])[N:21]=1)=[O:18])(=[O:15])=[O:14]

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 24526Chlorine

HCID 13321775HCID 13321775, compound

Product 1

HCID 20398788HCID 20398788, compound

Procedure

2.13 g of chlorine are introduced within 20 minutes into a solution of 11.37 g of N-(2-allyloxyphenylsulfonyl)-N'-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea in 100 ml of methylene chloride at a temperature of 0° C. The reaction mixture is stirred for a further 18 hours at room temperature. After addition of petroleum ether, the product is precipitated. Yield: 12.1 g of N-[2-(2,3-dichloropropyloxy)-phenylsulfonyl]-N'-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea with a melting point of 117°-118° C.

Workup

customthe product is precipitated

Sources & evidence

ORD record: ord-c64f3bc71e83475c9be30a83e2217f20
Source dataset: uspto-grants-1985_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04514212

Reaction notes

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