Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-(Bromomethyl)-4-propylbicyclo[2.2.2]octane | HCID 20398970 | — |
| Reactant | 3-Hydroxy-6-pentylbenzene-1,2-dicarbonitrile | HCID 20399039 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 20399003 | HCID 20399003 | — |
Reaction Steps
50 ml of dimethylformamide were added to 0.04 mole of 2,3-dicyano-4-pentylphenol, 0.2 mole of potassium carbonate and 0.04 mole of 4-propyl-1-bicyclo(2,2,2)-octylmethyl bromide. The mixture was stirred at 80° C. for 48 hours. The mixture was then cooled to room temperature and poured into 200 ml of water and the organic phase was extracted. The organic extract was washed with water and dried over magnesium sulfate. After the solvent had been evaporated off, the crude product was recrystallized several times. The pure product has a high melting point of 133.1° C. and a negative DCA.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04514317 |
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| Source dataset | uspto-grants-1985_04 |
|---|
| ORD ID | ord-6543fd1f774448baae67055298b1c141 |
|---|
| Source note | uspto-grants-1985_04 |
|---|
