HRID1981293

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID87287

Undecanoyl chloride

C11H21ClO

结构：Cl.OC1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)C1

HCID162982

1-{3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl}pyrrolidin-3-ol--hydrogen chloride (1/1)

C20H22ClF3N2OS

PRODUCTS

生成物

结构：CCCCCCCCCCC(=O)OC1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)C1

HCID20399166

未命名化合物

PROCEDURE

实验过程

According to the procedure of Example 5, 10.8 g of 2-trifluoromethyl-10-[3-(3-hydroxypyrrolidino)-propyl]-phenothiazine.hydrochloride and 6.2 g of undecanoylchloride were subjected to the reaction, to object the object as the free base. (Yield: 11.2 g)

WORKUP

后处理

customwere subjected to the reaction

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3ba16f6f5eb04b74bd681794a412e758
来源数据集: uspto-grants-1985_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04514395
来源说明: uspto-grants-1985_04

反应 SMILES

Cl.[F:2][C:3]([F:28])([F:27])[C:4]1[CH:17]=[CH:16][C:15]2[S:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[N:7]([CH2:18][CH2:19][CH2:20][N:21]3[CH2:25][CH2:24][CH:23]([OH:26])[CH2:22]3)[C:6]=2[CH:5]=1.[C:29](Cl)(=[O:40])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39]>>[F:28][C:3]([F:27])([F:2])[C:4]1[CH:17]=[CH:16][C:15]2[S:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[N:7]([CH2:18][CH2:19][CH2:20][N:21]3[CH2:25][CH2:24][CH:23]([O:26][C:29](=[O:40])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])[CH2:22]3)[C:6]=2[CH:5]=1