Methanol → HCID 13456634, compound

Participants

Reaction Steps

A mixture of 8.9 g (0.015 m) of the amide, 1 g (0.025 m) of sodium hydroxide and 100 ml of methanol was stirred at room temperature for 2 hours, then, poured into water. The quench was extracted with ethyl acetate. The extract was washed with water, dried and evaporated to give 4.4 g of 6-chloro-1-(4'-isobutylsulfonylphenyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepine.

Provenance & Evidence