Ethanol → HCID 70477288, compound

Participants

Reaction Steps

A solution of 0.460 g. (1.37 mmole) of 1-(4,4-diphenyl-3-butenyl)-3-pyrrolidineacetic acid in 30 ml. of absolute ethanol was reduced, using 0.15 g. of 10% palladium-on-carbon, for 1.5 hours at ambient temperature. The mixture was filtered and concentrated. A portion of the oily residue and one equivalent of maleic acid were mixed in methanol and concentrated to yield a solid which was recrystallized from isopropanol/ether to give 1-(4,4-diphenylbutyl)-3-pyrrolidineacetic acid maleate, m.p. 85°-87° C.

Provenance & Evidence