4-Toluenesulfonyl chloride → HCID 13313521, compound

Participants

Reaction Steps

A solution of 33.8 g of 2,2-dichloro-3,3-dimethylcyclopropane methanol in 200 ml of pyridine was cooled to 0° C., and 38.2 g of p-toluenesulfonyl chloride was added portionwise. The reaction mixture was left to stand for 12 hours in a refrigerator (0° C.), and then poured into 1 liter of ice water. The crystals precipitated were collected by filtration, washed with water, dried in the air, and washed with hexane to give 62 g of 2,2-dichloro-3,3-dimethylcyclopropylmethyl p-toluenesulfonate, the desired compound shown above. The melting point of the product was 96.5° to 97.5° C.

Provenance & Evidence