Ammonia → HCID 135598750, compound

HRID 1981425Notes

Reaction equation

HRID 1981425 reaction equation
[NH3:1].Cl.CO[N:5]=[CH:6][C:7]1[CH:15]=[C:11]([C:12]([OH:14])=[O:13])[C:10]([OH:16])=[CH:9][CH:8]=1>CO>[C:6]([C:7]1[CH:15]=[C:11]([C:12]([OH:14])=[O:13])[C:10]([OH:16])=[CH:9][CH:8]=1)(=[NH:5])[NH2:1]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 136387257HCID 136387257, compound

Product 1

HCID 135598750HCID 135598750, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a mixture of 40 ml of methanol and 20 ml of liquid ammonia, was added 4.0 g of 5-methoxyiminomethylsalicylic acid hydrochloride. The mixture was stirred overnight at room temperature. A colorless gelatinous substance precipitated from the reaction mixture was washed with methanol, and washed with a water-acetone (20 ml-80 ml) mixture to obtain 2.6 g of 5-amidinosalicylic acid.

Workup

  1. customA colorless gelatinous substance precipitated from the reaction mixture
  2. washwas washed with methanol
  3. washwashed with a water-acetone (20 ml-80 ml) mixture

Sources & evidence

ORD record
ord-07d7092d087346a8a1a5fb0df0b1c738
Source dataset
uspto-grants-1985_04
Patent number
US04514416

Reaction notes

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