HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 2-Nitro-3-Methylbenzotrichloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-Nitro-3-methyl benzal chloride | HCID 13573562 | — |
| Reactant | 1-(Chloromethyl)-3-methyl-2-nitrobenzene | HCID 13573563 | — |
| Catalyst | Dodecyltrimethylammonium chloride | HCID 8152 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | 2-Nitro-3-Methylbenzotrichloride | HCID 13573565 | — |
Reaction Steps
9.6 gms of 2-nitro-3-methyl benzal chloride (prepared by chlorination of 2-nitro-m-tolualdehyde with thionyl chloride), 9.6 gms of 2-nitro-3-methyl benzyl chloride, 0.6 gms of n-dodecyl trimethyl ammonium chloride, 160 ml of methylene chloride, 100 ml of carbon tetrachloride, 250 ml of 50% sodium hydroxide, and 10 gms of t-butyl alcohol were charged into a reaction vessel. The mixture was refluxed for 31/2 hours, cooled, solvent extracted, distilled and recrystallized to 16.0 gms of product as determined by GC-Mass spectral analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04593144 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-90f7aad27e7b4dfdbb6eadc44b9f7309 |
| Source note | uspto-grants-1986_06 |