HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 6-Hydroxyquinoline-5-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Methyl 6-hydroxyquinoline-5-carboxylate | HCID 19077292 | — |
| Product | 6-Hydroxyquinoline-5-carboxamide | HCID 21271480 | — |
Reaction Steps
6-Hydroxy-5-quinolinecarboxylic acid methyl ester is reacted with excess ammonia in a steel bomb for 12-18 hr. The excess ammonia is allowed to evaporate and the residue is crystallized from a suitable solvent to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04592866 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-adea3591a0a544e581b1cda96a5d5dae |
| Source note | uspto-grants-1986_06 |